Skip to calculator

Buffer capacity

Solve buffer capacity relationships quickly using core chemistry formulas.

Formula shown3 inputs definedUpdated Nov 2025By Automated Chemistry GeneratorFree, no sign-up

Quick Summary

Use this when you need:
  • Measure how robust a pharmaceutical buffer is against acid additions
  • Compare buffer recipes by simulating how much acid each can neutralize
  • Convert titration data (ΔpH vs. moles added) into a formal buffer capacity
You’ll need:Buffer capacity, Final pH, Initial pH
You’ll get:Amount of acid/base

Calculator Tool

How this is calculated

Formula:

β = Δn_{acid/base} / ΔpH

In plain language:

Buffer capacity β is defined as the amount (in moles) of strong acid or base required to shift the pH by one unit, so dividing the added amount by the observed pH change returns β.

The formula is always visible so you can verify the math and explain your numbers to anyone who asks.

Advertisement

What these terms mean

Amount of acid/base

Amount of acid/base used in the calculation.

Buffer capacity

Buffer capacity used in the calculation.

Final pH

Final pH used in the calculation.

Initial pH

Initial pH used in the calculation.

When to use this calculator

  • Measure how robust a pharmaceutical buffer is against acid additions
  • Compare buffer recipes by simulating how much acid each can neutralize
  • Convert titration data (ΔpH vs. moles added) into a formal buffer capacity
Advertisement